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Hops (Humulus lupulus L.) Herbal Treatment for Insomnia Scientific Evidence A sedative and hypnotic action has been attributed the 2-methyl-3-butene-2-ol molecule, which is a constituent of the hops plant (Harsel, et al 1982 and Wohlfart, et al 1983). Historical Use King George III used a pillow of hops to cure his insomnia, and many others carry on this tradition today. The mostly likely mechanism of action here is 2-methyl-3-butene-2-ol molecule, which is quite volatile and has proven sedative properties. References Harsel, R., et al. 1982. "The sedative-hypnotic principle of hops. 3. Communication: Contents of 2-methyl-3-butene-2-ol in hops and hops preparations." Planta Medica. 45:224-28. Wohlfart, R., R. Harsel, H. Schmidt. 1983. "The sedative-hypnotic principle of hops. 4. Communication: Pharmacology of 2-methyl-3-butene-2-ol." Planta Medica. 48:120-23. |
An outline of clinical studies that verify the effectiveness of herbal medications and supplements |