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Asthma The bronchi, airways of the lungs, are tubes surrounded by muscular walls. The cells lining the bronchi contain beta-adrenergic, cholinergic, and peptidergic receptors. When these receptors sense the presence of certain substances, they send a signal to the underlying muscles which tells them to contract or relax. Air flow is reduced when the bronchi narrow and increased when the bronchi expand. Beta-adrenergic receptors cause the muscles to relax, thereby increasing the flow of air into the lungs. Cholinergic and peptidergic receptors cause the muscles to contract, thereby decreasing the flow of air into the lungs. Mast cells in the bronchi can cause the muscles to contract, stimulate mucus secretions, and attract white blood cells when they release histamines and leukotrienes. During an asthma attack, the bronchi narrow and the tissue surrounding the bronchi swell from inflammation and secrete mucus into the airway, making it difficult for the individual to inhale. Causes of Asthma The contraction of the airways is often caused by abnormally sensitive cholinergic and peptidergic receptors. An asthma attack can be triggered by inhaled allergens such as pollen, dust mite particles, body secretions from cockroaches, and particles found on feathers. Other causes include: Cold air Viral infections Sensitivities to foods such as peanuts and shellfish Stress Anxiety Symptoms of Asthma The frequency and severity of asthma attacks can be quite different for different individuals. The first signs of an attack usually include shortness of breath, coughing, wheezing, and/or tightening of the chest. The duration of an attack can range from few minutes to a few days. Itching of the chest or neck can be an early warning sign. This is more common in children than in adults. Shortness of breath can become severe, resulting in anxiety. This anxiety can lead to sweating, a rapid pulse, and a feeling that there is pounding in the chest. Herbal Treatments for Asthma Boswellia (Boswellia serrata) Scientific Evidence from Clinical Trials A six-week, double-blind, placebo-controlled study involving 80 individuals with relatively mild asthma reported that the group taking 300 mg of boswellia 3 times daily experienced a reduction in the frequency of asthma attacks and improvements in objective measurements of breathing capacity that exceeded those from the placebo group (Gupta et al. 1998). References Gupta, I., V. Gupta, A. Parihar, et al. 1998. "Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study." Eur J Med Res. 3:511-514. |
An outline of clinical studies that verify the effectiveness of herbal medications and supplements |